NFL NFC West

San Francisco 49ers predictions & picks

Levi's® StadiumSan FranciscoSince 1946

2026 record: 7-1
NFC West: 1st
PPG: 29.4
Streak: W1
Last 5: Won 24–14 vs Denver Broncos · Sun, Oct 4 Won 32–29 at Seattle Seahawks · Sun, Oct 11 Won 23–17 vs Washington Commanders · Mon, Oct 19 Lost 20–29 at Atlanta Falcons · Sun, Oct 25 Won 38–17 vs Las Vegas Raiders · Sun, Nov 8

San Francisco 49ers next game

Wk 10

49ers @4:25 PM ET Sunday, November 15 AT&T Stadium, Arlington Cowboys

Best pick DAL +9.5−250 78% confidence See the prediction: 49ers at Cowboys

San Francisco 49ers 2026 schedule & results

Every pick graded once the game ends

WeekOpponentResult Our best pickGame page

Wk 1Thu, Sep 10Sep 10 @Los Angeles Rams Rams W27–7 —

Wk 2Sun, Sep 20Sep 20 vs Miami Dolphins Dolphins W35–13 —

Wk 3Sun, Sep 27Sep 27 vs Arizona Cardinals Cardinals W36–30 —

Wk 4Sun, Oct 4Oct 4 vs Denver Broncos Broncos W24–14 —

Wk 5Sun, Oct 11Oct 11 @Seattle Seahawks Seahawks W32–29 O 39.5−286✓ 49ers at Seahawks prediction

Wk 6Mon, Oct 19Oct 19 vs Washington Commanders Commanders W23–17 WAS +14.5−270✓ Commanders at 49ers prediction

Wk 7Sun, Oct 25Oct 25 @Atlanta Falcons Falcons L20–29 U 56.5−244✓ 49ers at Falcons prediction

Wk 9Sun, Nov 8Nov 8 vs Las Vegas Raiders Raiders W38–17 SF ML−455✓ Raiders at 49ers prediction

Wk 10Sun, Nov 15Nov 15 @Dallas Cowboys Cowboys 4:25 PM ET DAL +9.5−250 49ers at Cowboys prediction

Wk 11Sun, Nov 22Nov 22 vs Minnesota Vikings Vikings 8:20 PM ET Pick coming soon

San Francisco 49ers team stats

2026 regular season · 8 games · rank among 32 NFL teams

Offense

Points 29.4/ game 3rd

Total yards 376.8/ game 6th

Passing yards 241.5/ game 11th

Rushing yards 135.3/ game 7th

Third-down conversions 51.7% 2nd

Red-zone touchdowns 84.6% 1st

Giveaways 1.4/ game 18th

Time of possession 29:34 22nd

Defense

Points allowed 19.5/ game 6th

Yards allowed 291.9/ game 3rd

Passing yards allowed 211.0/ game 8th

Rushing yards allowed 80.9/ game 2nd

Takeaways 1.5/ game 7th

Sacks 1.9/ game 26th

Penalties 6.3/ game 6th

San Francisco 49ers leaders

2026 regular season

Passing Brock Purdy 1,980yds 17 TD · 5 INT · 69.1% comp. · 8 games

Rushing Christian McCaffrey 457yds 9 TD · 4.5 per carry · 8 games

Receiving George Kittle 483yds 38 catches · 5 TD · 8 games

Tackles Fred Warner 76 8 games

Sacks Keion White 3.5 7 games

Interceptions Renardo Green 4 6 passes defended · 7 games

San Francisco 49ers injury report

The current report: out, doubtful and questionable first

INACTIVE Enrique Cruz Jr. Coach's Decision

INACTIVE Kurtis RourkeQB Coach's Decision

INACTIVE Mike EvansWR Inactive for Week 9 vs. Las Vegas

INACTIVE Tatum BethuneLB Coach's Decision

OUT Gracen HaltonDT Ankle

QUESTIONABLE Deommodore LenoirCB Foot

QUESTIONABLE Renardo GreenCB Back

Reserve lists (IR / PUP) · 12

IRAusten PleasantsKnee

IRNickolas MartinLBHamstring

IRChristian KirkKnee - Meniscus

IRNate HobbsGroin

IRAlfred CollinsDTKnee

IRDarrick ForrestUndisclosed

IRJake TongesKnee - MCL

IRMikail KamaraKnee

IRNick ZakeljUndisclosed

IRSam OkuayinonuDTFoot

IRRicky PearsallKnee - PCL

PUPIsaac GuerendoPectoral

San Francisco 49ers picks record

Our best picks on their games, 2026 · pushes not counted

100.0% 4 won · 0 lostSmall sample so far. Picks never change once posted and are graded from the final score. Full track record

NFC West standings

Full NFL standings

#Team WLT W-L PCTPFPA DIFFSTRKSTK

1 San Francisco 49ers 49ers 710 7-1 .875 235156 +79 W1

2 Seattle Seahawks Seahawks 540 5-4 .556 202162 +40 W1

3 Los Angeles Rams Rams 540 5-4 .556 214181 +33 W3

4 Arizona Cardinals Cardinals 360 3-6 .333 178255 −77 L1

San Francisco 49ers FAQ

Who do the San Francisco 49ers play next?

Next up for the San Francisco 49ers: on the road at the Dallas Cowboys, Sunday, November 15, 4:25 PM ET. Our moneyline, spread and over/under picks for that game are on its prediction page.

What is the San Francisco 49ers’ record this season?

The San Francisco 49ers are 7-1, 1st in the NFC West: 5-0 at home and 2-1 on the road.

Who leads the San Francisco 49ers in passing yards?

Brock Purdy, with 1,980 passing yards in the 2026 regular season (17 TD · 5 INT · 69.1% comp. · 8 games).

Where do the San Francisco 49ers play their home games?

At Levi's® Stadium in San Francisco. The franchise dates from 1946.

What is the model’s record picking San Francisco 49ers games?

Its best pick is 4-0 in San Francisco 49ers games this season (100.0%, small sample). Picks never change once posted, and each one is graded from the final score.

NFC West rivals

All teams

Arizona Cardinals Los Angeles Rams Seattle Seahawks

San Francisco 49ers this week

The San Francisco 49ers are 7-1 and lead the NFC West by two and a half games over the Seattle Seahawks. Their last game was a 38–17 win over the Las Vegas Raiders at home on November 8. Their offense averages 29.4 points a game (3rd in the NFL), and their defense allows 19.5 (6th).

Next up, they visit the Dallas Cowboys at AT&T Stadium on Sunday, November 15 at 4:25 PM ET. At the sportsbooks, the 49ers are 3.5-point favorites, and the over/under is 55.5 points. Our moneyline, spread and over/under picks for the game are on the 49ers vs Cowboys prediction page. The rest of the week’s games are on the NFL Week 10 picks board.