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Las Vegas Raiders vs San Francisco 49ers prediction, picks and odds

Back to this week’s NFL picks NFL picks Week 9 Sunday, November 8 · 4:25 PM ET Levi's Stadium, Santa Clara
4-4 · Away
17–38 Final Predicted 24–27
6-1 · Home
Score by quarter
TeamQ1Q2Q3Q4T
LV0107017
SF14714338
RAIDERS 26% Pre-game win chance 74% 49ERS

SF by 3 · 51 points

Updated Nov 8, 7:48 PM ET

Raiders vs 49ers picks

3 picks · 49ers by 3 · 51 points · 2 of 3 won
MoneylineBest pick
SF MLodds up −455 Won 90%
The 49ers win the game.
Confidence90%
Model74.2% SportsbooksOdds82.4% Edge−8.2
Spread
LV +16.5−250 Lost 75%
The Raiders win, or lose by 16 points or fewer.
Confidence75%
Model68.4% SportsbooksOdds68.1% Edge+0.3
Total
Under 58odds up −227 Won 77%
The two teams score 57 or fewer points between them (exactly 58 is a push).
Confidence77%
Model73.0% SportsbooksOdds69.9% Edge+3.1

Reading a pick: Sportsbooks is the win chance built into the odds when the pick went up, Model is our model’s own number, and Edge is the gap between them. Every pick is graded once the game is final.

Predicted score by quarter The model’s most likely score in each quarter, away team first
TeamQ1Q2Q3Q41st halfFinal
Raiders0100141024
49ers017371727
Most likely final scoresLV 24–27 SF 0.9%LV 20–23 SF 0.7%LV 17–20 SF 0.6%
Projected box score Model only Built from 20 full box scores per team · not a betting line
Raiders49ers

Offense

297▼ 240 Total yards ▲ 414376
216= 216 Passing yards ▼ 224238
81▼ 24 Rushing yards ▲ 190138
18▼ 14 First downs ▲ 2722

Scoring

3▼ 2 Touchdowns ▲ 53
2▼ 1 Passing touchdowns = 22
1= 1 Rushing touchdowns ▲ 21
1= 1 Field goals made ▼ 12

Ball security

1▲ 5 Turnovers = 11
1▲ 3 Interceptions thrown = 11
1▲ 2 Fumbles lost ▼ 01
2▼ 0 Sacks allowed ▼ 12
51▼ 29 Penalty yards ▲ 5954
Team stat picks The model’s own lines on each team’s yards and first downs · no sportsbook odds
Total yards Over 250.5 Proj. 297 72% Lost · 240
Passing yards Over 174.5 Proj. 216 72% Won · 216
Rushing yards Over 52.5 Proj. 81 72% Lost · 24
First downs Over 15.5 Proj. 18 71% Lost · 14
Total yards Over 329.5 Proj. 376 72% Won · 414
Passing yards Over 196.5 Proj. 238 72% Won · 224
Rushing yards Over 109.5 Proj. 138 72% Won · 190
First downs Over 19.5 Proj. 22 72% Won · 27
Key players Projected lines for each team’s quarterback, running back and top receivers
Raiders
QB Kirk Cousins22/34 · 216 pass yds · 2.0 TD · 0.6 INT 216pass yds
RB Mike Washington9 carries · 43 rush yds · 0.3 TD · 1 rec 43rush yds
WR/TE Brock Bowers6 rec · 69 yds · 0.8 TD 69rec yds
WR/TE Ashton Jeanty4 rec · 40 yds · 0.2 TD 40rec yds
49ers
QB Brock Purdy21/31 · 238 pass yds · 2.0 TD · 0.7 INT 238pass yds
RB Christian McCaffrey13 carries · 62 rush yds · 0.8 TD · 5 rec 62rush yds
WR/TE Mike Evans5 rec · 72 yds · 0.4 TD 72rec yds
WR/TE George Kittle6 rec · 65 yds · 0.8 TD 65rec yds

The San Francisco 49ers beat the Las Vegas Raiders 38–17 in NFL Week 9 of the 2026 season, on Sunday, November 8 at 4:25 PM ET, at Levi's Stadium, Santa Clara. The moneyline had the Raiders at +360 and the 49ers at −476.

Our model predicted a final score of Raiders 24, 49ers 27. Its picks: the 49ers to win (−455), won; the Raiders +16.5 (−250), lost; under 58 points (−227), won. The best pick was the 49ers to win, at 90% confidence.