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Indianapolis Colts vs Jacksonville Jaguars prediction, picks and odds

Back to this week’s NFL picks NFL picks Week 8 Sunday, November 1 · 1:00 PM ET EverBank Stadium, Jacksonville
2-5 · Away
7–42 Final Predicted 24–27
4-2 · Home
Score by quarter
TeamQ1Q2Q3Q4T
IND00707
JAX72114042
COLTS 28% Pre-game win chance 72% JAGUARS

JAX by 3 · 51 points

Updated Nov 1, 4:17 PM ET

Colts vs Jaguars picks

3 picks · Jaguars by 3 · 51 points · 2 of 3 won
MoneylineBest pick
JAX MLodds down −500 Won 82%
The Jaguars win the game.
Confidence82%
Model72.2% SportsbooksOdds78.7% Edge−6.5
Spread
IND +14.5odds up −189 Lost 75%
The Colts win, or lose by 14 points or fewer.
Confidence75%
Model68.2% SportsbooksOdds68.1% Edge+0.1
Total
Over 40.5odds up −217 Won 76%
The two teams score 41 or more points between them.
Confidence76%
Model68.5% SportsbooksOdds67.7% Edge+0.8

Reading a pick: Sportsbooks is the win chance built into the odds when the pick went up, Model is our model’s own number, and Edge is the gap between them. Every pick is graded once the game is final.

Predicted score by quarter The model’s most likely score in each quarter, away team first
TeamQ1Q2Q3Q41st halfFinal
Colts77731424
Jaguars737101027
Most likely final scoresIND 24–27 JAX 0.9%IND 20–23 JAX 0.8%IND 17–24 JAX 0.6%
Projected box score Model only Built from 20 full box scores per team · not a betting line
ColtsJaguars

Offense

315▼ 243 Total yards ▲ 366347
219▼ 134 Passing yards ▼ 183230
96▲ 109 Rushing yards ▲ 183117
19▼ 17 First downs ▼ 1820

Scoring

3▼ 1 Touchdowns ▲ 63
2▼ 1 Passing touchdowns ▲ 32
1▼ 0 Rushing touchdowns ▲ 21
1▼ 0 Field goals made ▼ 02

Ball security

1▲ 3 Turnovers = 11
1▲ 2 Interceptions thrown ▼ 01
1= 1 Fumbles lost = 11
2▲ 4 Sacks allowed ▲ 32
52▲ 54 Penalty yards ▲ 6554
Team stat picks The model’s own lines on each team’s yards and first downs · no sportsbook odds
Total yards Over 268.5 Proj. 315 72% Lost · 243
Passing yards Over 177.5 Proj. 219 72% Lost · 134
Rushing yards Over 67.5 Proj. 96 72% Won · 109
First downs Over 16.5 Proj. 19 69% Won · 17
Total yards Over 300.5 Proj. 347 72% Won · 366
Passing yards Over 188.5 Proj. 230 72% Lost · 183
Rushing yards Over 88.5 Proj. 117 72% Won · 183
First downs Over 17.5 Proj. 20 70% Won · 18
Key players Projected lines for each team’s quarterback, running back and top receivers
Colts
QB Daniel Jones22/35 · 219 pass yds · 2.0 TD · 0.9 INT 219pass yds
RB Jonathan Taylor17 carries · 65 rush yds · 0.8 TD · 2 rec 65rush yds
WR/TE Josh Downs4 rec · 53 yds · 0.0 TD 53rec yds
WR/TE Keenan Allen5 rec · 50 yds · 0.7 TD 50rec yds
Jaguars
QB Trevor Lawrence20/31 · 230 pass yds · 2.0 TD · 0.7 INT 230pass yds
RB Bhayshul Tuten15 carries · 67 rush yds · 0.5 TD · 2 rec 67rush yds
WR/TE Parker Washington4 rec · 68 yds · 0.6 TD 68rec yds
WR/TE Brenton Strange4 rec · 46 yds · 0.1 TD 46rec yds

The Jacksonville Jaguars beat the Indianapolis Colts 42–7 in NFL Week 8 of the 2026 season, on Sunday, November 1 at 1:00 PM ET, at EverBank Stadium, Jacksonville. The moneyline had the Colts at +390 and the Jaguars at −526.

Our model predicted a final score of Colts 24, Jaguars 27. Its picks: the Jaguars to win (−500), won; the Colts +14.5 (−189), lost; over 40.5 points (−217), won. The best pick was the Jaguars to win, at 82% confidence.