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Carolina Panthers vs New Orleans Saints prediction, picks and odds

Back to the NFL Week 10 picks NFL picks Week 10 Sunday, November 15 · 1:00 PM ET Caesars Superdome, New Orleans
Panthers
Away · 3-5ML odds down +108
1:00PM Kickoff Sun, Nov 15 · ET
Saints
ML odds up −132Home · 3-5
SpreadNO −2.5
Total48.5 points
Kickoff in3d 21h

Caesars Superdome

Predictions3 Comparison Recent games Standings Head-to-head Odds Injuries
Updated 3:17 PM ET

Panthers vs Saints picks

3 picks · Saints by 3 · 37 points
Moneyline
NO MLodds down −139 52%
The Saints win the game.
Confidence52%
Model51.2% SportsbooksOdds52.2% Edge−1.0
SpreadBest pick
CAR +5.5odds up −192 78%
The Panthers win, or lose by five points or fewer.
Confidence78%
Model67.2% SportsbooksOdds67.2% Edge0.0
Total
Under 54.5odds up −227 77%
The two teams score 54 or fewer points between them.
Confidence77%
Model72.6% SportsbooksOdds67.2% Edge+5.4

Reading a pick: Sportsbooks is the win chance built into the odds when the pick went up, Model is our model’s own number, and Edge is the gap between them. Every pick is graded once the game is final.

Predicted score by quarter The model’s most likely score in each quarter, away team first
TeamQ1Q2Q3Q41st halfFinal
Panthers37071017
Saints0100101020
Most likely final scoresCAR 17–20 NO 0.8%CAR 20–23 NO 0.8%CAR 24–27 NO 0.7%
Projected box score Model only Built from 20 full box scores per team · not a betting line
PanthersSaints

Offense

346 Total yards 327
235 Passing yards 218
111 Rushing yards 109
20 First downs 20

Scoring

2 Touchdowns 2
1 Passing touchdowns 1
1 Rushing touchdowns 1
1 Field goals made 2

Ball security

1 Turnovers 1
1 Interceptions thrown 1
1 Fumbles lost 1
3 Sacks allowed 2
56 Penalty yards 51
Team stat picks The model’s own lines on each team’s yards and first downs · no sportsbook odds
Total yards Over 299.5 Proj. 346 72%
Passing yards Over 193.5 Proj. 235 72%
Rushing yards Over 82.5 Proj. 111 72%
First downs Over 17.5 Proj. 20 70%
Total yards Over 280.5 Proj. 327 72%
Passing yards Over 175.5 Proj. 217 72%
Rushing yards Over 80.5 Proj. 109 72%
First downs Over 17.5 Proj. 20 73%
Key players Projected lines for each team’s quarterback, running back and top receivers
Panthers
QB Bryce Young21/34 · 235 pass yds · 1.0 TD · 0.7 INT 235pass yds
RB Chuba Hubbard20 carries · 93 rush yds · 0.8 TD · 3 rec 93rush yds
WR/TE Tetairoa McMillan5 rec · 72 yds · 0.3 TD 72rec yds
WR/TE Darren Waller3 rec · 38 yds · 0.2 TD 38rec yds
Saints
QB Tyler Shough23/35 · 218 pass yds · 1.0 TD · 0.7 INT 218pass yds
RB Kendre Miller11 carries · 32 rush yds · 0.3 TD · 2 rec 32rush yds
WR/TE Chris Olave6 rec · 82 yds · 0.1 TD 82rec yds
WR/TE Alvin Kamara3 rec · 25 yds · 0.1 TD 25rec yds

The Carolina Panthers visit the New Orleans Saints in NFL Week 10 of the 2026 season, on Sunday, November 15 at 1:00 PM ET, at Caesars Superdome, New Orleans. The Panthers come in at 3-5 and the Saints at 3-5. The moneyline has the Panthers at +108 and the Saints at −132.

Our model predicts a final score of Panthers 17, Saints 20. Its picks: the Saints to win (−139); the Panthers +5.5 (−192); under 54.5 points (−227). The best pick is the Panthers +5.5, at 78% confidence.