Skip to content
No games live 2026 season · Week 10 of 18
Odds: American
English 21+ · Play responsibly
Saved games Sign up

Ohio State vs Indiana prediction, picks and odds

Back to the college football picks NCAA FBS picks Week 7 Saturday, October 17 · 12:00 PM ET
5-1 · Away
19–15 Final Predicted 21–28
6-0 · Home
Score by quarter
TeamQ1Q2Q3Q4T
OSU373619
IU070815
OHIO STATE 44% Pre-game win chance 56% INDIANA

IU by 7 · 49 points

Updated Oct 17, 3:58 PM ET

Ohio State vs Indiana picks

3 picks · Indiana by 7 · 49 points · 1 of 3 won
Moneyline
IU MLodds down +110 Lost 62%
Indiana wins the game.
Confidence62%
Model54.0% SportsbooksOdds37.9% Edge+16.1
Spread
IU +10.5odds down −345 Won 86%
Indiana wins, or loses by 10 points or fewer.
Confidence86%
Model80.9% SportsbooksOdds70.5% Edge+10.4
TotalBest pick
Over 42.5odds up −256 Lost 79%
The two teams score 43 or more points between them.
Confidence79%
Model71.1% SportsbooksOdds70.4% Edge+0.7

Reading a pick: Sportsbooks is the win chance built into the odds when the pick went up, Model is our model’s own number, and Edge is the gap between them. Every pick is graded once the game is final.

Predicted score by quarter The model’s most likely score in each quarter, away team first
TeamQ1Q2Q3Q41st halfFinal
Ohio State7077721
Indiana770141428
Most likely final scoresOSU 21–28 IU 0.7%OSU 28–31 IU 0.6%OSU 21–24 IU 0.6%
Projected box score Model only Built from 20 full box scores per team · not a betting line
Ohio StateIndiana

Offense

376▼ 313 Total yards ▲ 369351
260▼ 235 Passing yards ▲ 296196
116▼ 78 Rushing yards ▼ 73155
20▼ 19 First downs ▼ 1719

Scoring

3▼ 2 Touchdowns ▼ 23
2= 2 Passing touchdowns ▼ 12
1▼ 0 Rushing touchdowns = 11
0▲ 2 Field goals made ▼ 02

Ball security

1▲ 2 Turnovers ▲ 21
1▲ 2 Interceptions thrown ▼ 01
0= 0 Fumbles lost ▲ 21
0 Sacks allowed 0
47▲ 50 Penalty yards = 4242
Team stat picks The model’s own lines on each team’s yards and first downs · no sportsbook odds
Total yards Over 302.5 Proj. 376 72% Won · 313
Passing yards Over 202.5 Proj. 260 72% Won · 235
Rushing yards Over 63.5 Proj. 116 72% Won · 78
First downs Over 16.5 Proj. 20 70% Won · 19
Total yards Over 278.5 Proj. 352 72% Won · 369
Passing yards Over 139.5 Proj. 196 72% Won · 296
Rushing yards Over 102.5 Proj. 155 72% Lost · 73
First downs Over 14.5 Proj. 19 74% Won · 17
Key players Projected lines for each team’s quarterback, running back and top receivers
Ohio State
QB Julian Sayin18/27 · 227 pass yds · 1.7 TD · 0.3 INT 227pass yds
RB Bo Jackson13 carries · 54 rush yds · 0.3 TD · 2 rec 54rush yds
WR/TE Jeremiah Smith8 rec · 117 yds · 1.1 TD 117rec yds
WR/TE Devin Mccuin3 rec · 36 yds · 0.3 TD 36rec yds
Indiana
QB Josh Hoover15/24 · 185 pass yds · 1.8 TD · 0.0 INT 185pass yds
RB Lee Beebe15 carries · 64 rush yds · 0.4 TD · 1 rec 64rush yds
WR/TE Nick Marsh5 rec · 72 yds · 0.6 TD 72rec yds
WR/TE Charlie Becker5 rec · 72 yds · 0.8 TD 72rec yds

Ohio State beat Indiana 19–15 in college football Week 7, on Saturday, October 17 at 12:00 PM ET. The moneyline had Ohio State at −164 and Indiana at +121.

Our model predicted a final score of Ohio State 21, Indiana 28. Its picks: Indiana to win (+110), lost; Indiana +10.5 (−345), won; over 42.5 points (−256), lost. The best pick was over 42.5 points, at 79% confidence.