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No games live 2026 season · Week 10 of 18
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Indianapolis Colts vs Minnesota Vikings prediction, picks and odds

Back to this week’s NFL picks NFL picks Week 7 Sunday, October 25 · 1:00 PM ET U.S. Bank Stadium, Minneapolis
2-4 · Away
10–16 Final Predicted 17–20
5-0 · Home
Score by quarter
TeamQ1Q2Q3Q4T
IND730010
MIN0601016
COLTS 34% Pre-game win chance 66% VIKINGS

MIN by 3 · 37 points

Updated Oct 25, 3:57 PM ET

Colts vs Vikings picks

3 picks · Vikings by 3 · 37 points · 2 of 3 won
MoneylineBest pick
MIN MLodds down −333 Won 82%
The Vikings win the game.
Confidence82%
Model65.9% SportsbooksOdds71.7% Edge−5.8
Spread
IND +12.5odds up −244 Won 76%
The Colts win, or lose by 12 points or fewer.
Confidence76%
Model70.0% SportsbooksOdds68.3% Edge+1.7
Total
Over 36odds down −263 Lost 77%
The two teams score 37 or more points between them (exactly 36 is a push).
Confidence77%
Model72.4% SportsbooksOdds68.9% Edge+3.5

Reading a pick: Sportsbooks is the win chance built into the odds when the pick went up, Model is our model’s own number, and Edge is the gap between them. Every pick is graded once the game is final.

Predicted score by quarter The model’s most likely score in each quarter, away team first
TeamQ1Q2Q3Q41st halfFinal
Colts0737717
Vikings0100101020
Most likely final scoresIND 17–20 MIN 0.9%IND 24–27 MIN 0.8%IND 17–24 MIN 0.7%
Projected box score Model only Built from 20 full box scores per team · not a betting line
ColtsVikings

Offense

284▼ 218 Total yards ▼ 275317
180▼ 64 Passing yards ▼ 139199
104▲ 154 Rushing yards ▲ 136118
17▼ 15 First downs ▼ 1718

Scoring

2▼ 1 Touchdowns ▼ 12
1▼ 0 Passing touchdowns = 11
1= 1 Rushing touchdowns ▼ 01
1= 1 Field goals made ▲ 32

Ball security

1= 1 Turnovers ▼ 01
1= 1 Interceptions thrown ▼ 01
1▼ 0 Fumbles lost ▼ 01
3▲ 4 Sacks allowed ▲ 32
51▼ 46 Penalty yards ▼ 2452
Team stat picks The model’s own lines on each team’s yards and first downs · no sportsbook odds
Total yards Over 237.5 Proj. 284 72% Lost · 218
Passing yards Over 138.5 Proj. 180 72% Lost · 64
Rushing yards Over 75.5 Proj. 104 72% Won · 154
First downs Over 14.5 Proj. 17 70% Won · 15
Total yards Over 270.5 Proj. 317 72% Won · 275
Passing yards Over 157.5 Proj. 199 72% Lost · 139
Rushing yards Over 89.5 Proj. 118 72% Won · 136
First downs Over 14.5 Proj. 18 75% Won · 17
Key players Projected lines for each team’s quarterback, running back and top receivers
Colts
QB Daniel Jones18/32 · 180 pass yds · 1.0 TD · 0.8 INT 180pass yds
RB Jonathan Taylor19 carries · 76 rush yds · 0.8 TD · 2 rec 76rush yds
WR/TE Tyler Warren5 rec · 40 yds · 0.7 TD 40rec yds
WR/TE Keenan Allen4 rec · 38 yds · 0.3 TD 38rec yds
Vikings
QB Kyler Murray16/25 · 186 pass yds · 0.4 TD · 0.7 INT 186pass yds
RB Aaron Jones18 carries · 84 rush yds · 0.7 TD · 3 rec 84rush yds
WR/TE Jordan Addison3 rec · 52 yds · 0.3 TD 52rec yds
WR/TE T.J. Hockenson5 rec · 48 yds · 0.2 TD 48rec yds

The Minnesota Vikings beat the Indianapolis Colts 16–10 in NFL Week 7 of the 2026 season, on Sunday, October 25 at 1:00 PM ET, at U.S. Bank Stadium, Minneapolis. The moneyline had the Colts at +270 and the Vikings at −345.

Our model predicted a final score of Colts 17, Vikings 20. Its picks: the Vikings to win (−333), won; the Colts +12.5 (−244), won; over 36 points (−263), lost. The best pick was the Vikings to win, at 82% confidence.