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No games live 2026 season · Week 10 of 18
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Los Angeles Chargers vs Kansas City Chiefs prediction, picks and odds

Back to this week’s NFL picks NFL picks Week 6 Sunday, October 18 · 4:25 PM ET Arrowhead Stadium, Kansas City
0-5 · Away
6–22 Final Predicted 17–20
4-0 · Home
Score by quarter
TeamQ1Q2Q3Q4T
LAC30306
KC9100322
CHARGERS 32% Pre-game win chance 68% CHIEFS

KC by 3 · 37 points

Updated Oct 18, 7:54 PM ET

Chargers vs Chiefs picks

3 picks · Chiefs by 3 · 37 points · 1 of 3 won
MoneylineBest pick
KC ML−417 Won 90%
The Chiefs win the game.
Confidence90%
Model67.7% SportsbooksOdds79.2% Edge−11.5
Spread
LAC +15.5odds down −278 Lost 79%
The Chargers win, or lose by 15 points or fewer.
Confidence79%
Model73.7% SportsbooksOdds68.9% Edge+4.8
Total
Over 36.5odds up −222 Lost 76%
The two teams score 37 or more points between them.
Confidence76%
Model68.1% SportsbooksOdds68.9% Edge−0.8

Reading a pick: Sportsbooks is the win chance built into the odds when the pick went up, Model is our model’s own number, and Edge is the gap between them. Every pick is graded once the game is final.

Predicted score by quarter The model’s most likely score in each quarter, away team first
TeamQ1Q2Q3Q41st halfFinal
Chargers0773717
Chiefs07310720
Most likely final scoresLAC 17–20 KC 1.0%LAC 20–23 KC 0.8%LAC 17–24 KC 0.7%
Projected box score Model only Built from 20 full box scores per team · not a betting line
ChargersChiefs

Offense

303▼ 259 Total yards ▲ 422329
190▼ 186 Passing yards ▲ 272203
113▼ 73 Rushing yards ▲ 150126
18▼ 15 First downs ▲ 2219

Scoring

2▼ 0 Touchdowns = 22
1▼ 0 Passing touchdowns ▼ 01
1▼ 0 Rushing touchdowns ▲ 21
1▲ 2 Field goals made ▲ 32

Ball security

1▲ 2 Turnovers ▲ 21
1= 1 Interceptions thrown = 11
1= 1 Fumbles lost = 11
2▲ 4 Sacks allowed ▼ 02
53▲ 59 Penalty yards ▲ 8955
Team stat picks The model’s own lines on each team’s yards and first downs · no sportsbook odds
Total yards Over 256.5 Proj. 303 72% Won · 259
Passing yards Over 148.5 Proj. 190 72% Won · 186
Rushing yards Over 84.5 Proj. 113 72% Lost · 73
First downs Over 15.5 Proj. 18 73% Lost · 15
Total yards Over 282.5 Proj. 329 72% Won · 422
Passing yards Over 161.5 Proj. 203 72% Won · 272
Rushing yards Over 97.5 Proj. 126 72% Won · 150
First downs Over 16.5 Proj. 19 70% Won · 22
Key players Projected lines for each team’s quarterback, running back and top receivers
Chargers
QB Justin Herbert20/32 · 190 pass yds · 1.0 TD · 0.8 INT 190pass yds
RB Omarion Hampton14 carries · 48 rush yds · 0.8 TD · 1 rec 48rush yds
WR/TE Tre Harris3 rec · 52 yds · 0.0 TD 52rec yds
WR/TE Keaton Mitchell3 rec · 16 yds · 0.3 TD 16rec yds
Chiefs
QB Patrick Mahomes19/30 · 203 pass yds · 1.0 TD · 0.7 INT 203pass yds
RB Kenneth Walker III21 carries · 105 rush yds · 0.8 TD · 3 rec 105rush yds
WR/TE Travis Kelce4 rec · 50 yds · 0.2 TD 50rec yds
WR/TE Xavier Worthy3 rec · 27 yds · 0.1 TD 27rec yds

The Kansas City Chiefs beat the Los Angeles Chargers 22–6 in NFL Week 6 of the 2026 season, on Sunday, October 18 at 4:25 PM ET, at Arrowhead Stadium, Kansas City. The moneyline had the Chargers at +330 and the Chiefs at −417.

Our model predicted a final score of Chargers 17, Chiefs 20. Its picks: the Chiefs to win (−417), won; the Chargers +15.5 (−278), lost; over 36.5 points (−222), lost. The best pick was the Chiefs to win, at 90% confidence.