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No games live 2026 season · Week 10 of 18
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Buffalo Bills vs Las Vegas Raiders prediction, picks and odds

Back to this week’s NFL picks NFL picks Week 6 Sunday, October 18 · 4:25 PM ET Allegiant Stadium, Las Vegas
4-1 · Away
33–30 Final Predicted 23–20
3-2 · Home
Score by quarter
TeamQ1Q2Q3Q4T
BUF310101033
LV7601730
BILLS 69% Pre-game win chance 31% RAIDERS

BUF by 3 · 43 points

Updated Oct 18, 7:54 PM ET

Bills vs Raiders picks

3 picks · Bills by 3 · 43 points · 2 of 3 won
Moneyline
BUF ML−250 Won 87%
The Bills win the game.
Confidence87%
Model69.4% SportsbooksOdds69.1% Edge+0.3
SpreadBest pick
BUF +1.5odds up −278 Won 78%
The Bills win, or lose by one point or fewer.
Confidence78%
Model71.7% SportsbooksOdds71.5% Edge+0.2
Total
Under 60.5odds up −250 Lost 77%
The two teams score 60 or fewer points between them.
Confidence77%
Model76.1% SportsbooksOdds70.4% Edge+5.7

Reading a pick: Sportsbooks is the win chance built into the odds when the pick went up, Model is our model’s own number, and Edge is the gap between them. Every pick is graded once the game is final.

Predicted score by quarter The model’s most likely score in each quarter, away team first
TeamQ1Q2Q3Q41st halfFinal
Bills713032023
Raiders010371020
Most likely final scoresBUF 23–20 LV 0.8%BUF 27–24 LV 0.7%BUF 30–27 LV 0.6%
Projected box score Model only Built from 20 full box scores per team · not a betting line
BillsRaiders

Offense

379▼ 345 Total yards ▲ 378321
227▲ 242 Passing yards ▲ 313230
152▼ 103 Rushing yards ▼ 6591
22▲ 23 First downs ▲ 2520

Scoring

3= 3 Touchdowns ▲ 32
2= 2 Passing touchdowns ▲ 21
1= 1 Rushing touchdowns = 11
1▲ 4 Field goals made ▲ 32

Ball security

1▼ 0 Turnovers = 11
1▼ 0 Interceptions thrown = 11
1▼ 0 Fumbles lost ▼ 01
2= 2 Sacks allowed ▼ 02
55▲ 77 Penalty yards ▲ 6251
Team stat picks The model’s own lines on each team’s yards and first downs · no sportsbook odds
Total yards Over 332.5 Proj. 379 72% Won · 345
Passing yards Over 185.5 Proj. 227 72% Won · 242
Rushing yards Over 123.5 Proj. 152 72% Lost · 103
First downs Over 19.5 Proj. 22 70% Won · 23
Total yards Over 274.5 Proj. 321 72% Won · 378
Passing yards Over 188.5 Proj. 229 72% Won · 313
Rushing yards Over 62.5 Proj. 91 72% Won · 65
First downs Over 17.5 Proj. 20 71% Won · 25
Key players Projected lines for each team’s quarterback, running back and top receivers
Bills
QB Josh Allen20/30 · 227 pass yds · 2.0 TD · 0.7 INT 227pass yds
RB James Cook19 carries · 103 rush yds · 0.3 TD · 2 rec 103rush yds
WR/TE Khalil Shakir4 rec · 49 yds · 0.0 TD 49rec yds
WR/TE Ty Johnson4 rec · 47 yds · 0.0 TD 47rec yds
Raiders
QB Kirk Cousins22/35 · 230 pass yds · 1.0 TD · 0.7 INT 230pass yds
RB Ashton Jeanty16 carries · 65 rush yds · 0.0 TD · 4 rec 65rush yds
WR/TE Brock Bowers7 rec · 83 yds · 0.5 TD 83rec yds
WR/TE Michael Mayer4 rec · 31 yds · 0.1 TD 31rec yds

The Buffalo Bills beat the Las Vegas Raiders 33–30 in NFL Week 6 of the 2026 season, on Sunday, October 18 at 4:25 PM ET, at Allegiant Stadium, Las Vegas. The moneyline had the Bills at −238 and the Raiders at +195.

Our model predicted a final score of Bills 23, Raiders 20. Its picks: the Bills to win (−250), won; the Bills +1.5 (−278), won; under 60.5 points (−250), lost. The best pick was the Bills +1.5, at 78% confidence.